Adobe InDesign
Professional page layout and publishing
InDesign is Adobe's layout application for brochures, magazines, reports and print-ready documents. It is the standard for typesetting but has a steep learning curve for casual users.
Simple desktop publishing from Microsoft
Microsoft Publisher is a basic layout application bundled with some Office 365 plans, aimed at simple flyers, newsletters, and brochures. It's a familiar low-cost option for Windows users.

Professional page layout and publishing
InDesign is Adobe's layout application for brochures, magazines, reports and print-ready documents. It is the standard for typesetting but has a steep learning curve for casual users.
Professional desktop publishing software
Affinity Publisher handles multi-page layouts, master pages, and print-ready output without a subscription. It integrates with Affinity Photo and Designer for a full creative suite.
Template-first graphic design
Canva makes design approachable with templates and drag-and-drop editing for social, decks and print.
Open-source page layout and desktop publishing
Scribus is a free DTP application supporting CMYK color, ICC color management, and professional print output. It's used by hobbyists and budget-conscious publishers for layout work.
Brand templating and design automation platform
Marq (formerly Lucidpress) lets teams create and lock branded templates for flyers, reports and social content. It focuses on brand consistency and easy non-designer editing rather than pro-level typesetting.
AI presentations from a prompt
Gamma generates entire presentations, documents and webpages from a short prompt or outline. It writes the content, designs the slides and picks the imagery — you just edit the result.